Tirzepatide

A once-weekly injection designed to work on both GLP-1 and GIP pathways, offering a dual-action approach to medically guided weight loss.

Tirzepatide

A once-weekly injection designed to work on both GLP-1 and GIP pathways, offering a dual-action approach to medically guided weight loss.
$399/mo
HSA / FSA Eligible

Same-day assessment and free 2-day shipping

Premium personalized blend that goes beyond Semaglutide's single-hormone approach, targeting both GLP-1 and GIP.

Each batch of medication undergoes quality testing

100% online care
Doctor-prescribed
Pharmacy-prepared
Same-day assessment
Free shipping
24/7 support
100% online care
Doctor-prescribed
Pharmacy-prepared
Same-day assessment
Free shipping
24/7 support
What is Tirzepatide?

Tirzepatide is a dual-action GLP-1 medication that works with two of your body’s natural hormones, GLP-1 and GIP, to help regulate appetite and support weight loss. Willow’s compounded formulation is designed with your doctor and personalized to your health profile and goals.

A personalized plan can help you stay on track. Your doctor can adjust your treatment as your needs change, and your Care Team is available 24/7. It’s your treatment, made for you.

Compounded tirzepatide is not approved by the FDA, and the FDA does not review compounded medications for safety, effectiveness, or quality. These medications are prepared by state-licensed compounding pharmacies that operate under state board of pharmacy oversight and are required to meet USP compounding standards.

What is the difference between Semaglutide and Tirzepatide?

Semaglutide and tirzepatide are both medications used for weight loss, but they have distinct differences.

Semaglutide is a GLP-1 receptor agonist, which helps to regulate blood sugar by enhancing insulin secretion, slowing gastric emptying, and promoting satiety.

Tirzepatide is a formula that targets both GLP-1 and GIP, the two key incretin hormones, for a dual-action approach to glucose control and weight loss.

The Willow difference

US-licensed doctors
Transparent pricing, no hidden fees
Needle-free options
24/7 human support
Zero judgment
Others
Nurse practitioners or physician assistants
Add-on fees for visits or follow-ups
Injectable only
AI-powered support
Comes with a lecture

Tablet and injectable treatment options

Personalized tablets and injectable plans guided by licensed doctors, designed to put choice and confidence back in your hands.

The science behind Tirzepatide

When you eat, the food stimulates your gut to release the GLP-1 hormone. GLP-1 helps lower blood glucose (blood sugar) by triggering insulin release. Insulin helps blood glucose enter your body’s cells for later energy use.

In some people, the gut doesn't make enough natural GLP-1, or the brain isn't sensitive to it.

Tirzepatide is a synthetic GLP-1 RA (receptor agonist). A drug that works as an agonist activates the same cell receptors as the body’s natural hormones. Tirzepatide works in the gut like the body’s natural GLP-1, slowing digestion, curbing hunger, and signaling fullness to the brain.

How does it feel to take Tirzepatide?

Willow patients report:

Fewer random snack cravings throughout the day

Smaller portions feeling just as satisfying as large ones used to

The feeling of being full lasting longer after meals

Getting started with Willow

Three simple steps to weight loss care

1
Assessment
and review
FSA & HSA eligible
Answer a few questions about your health and goals. A US-licensed physician reviews your assessment, usually within 24 hours. If treatment is right for you, they'll confirm your prescription.
FSA & HSA eligible
2
Preparation
and shipping
Your prescription is prepared by trusted US pharmacy partners. It ships with tracking, so you always know where it is.
FSA & HSA eligible
3
Delivery
and support
Your treatment arrives in discreet packaging. From there, you'll have unlimited doctor messaging and 24/7 Care Team support.
FSA & HSA eligible

Getting started with Willow

Three simple steps to weight loss care
1
Assessment and review
Answer a few questions about your health and goals. A US-licensed physician reviews your assessment, usually within 24 hours. If treatment is right for you, they'll confirm your prescription.
FSA & HSA eligible
2
Preparation and shipping
Your prescription is prepared by trusted US pharmacy partners. It ships with tracking, so you always know where it is.
FSA & HSA eligible
3
Delivery and support
Your treatment arrives in discreet packaging. From there, you'll have unlimited doctor messaging and 24/7 Care Team support.
FSA & HSA eligible

Prescribed by U.S. licensed doctors

Willow care is led by experienced, U.S. licensed doctors who guide treatments with intention, expertise, and ongoing support.

Personalized care on your time

No office visits. 100% online. Free, regular follow-ups from your Willow Care Team.

Prepared bylicensed U.S. pharmacies

Your medication is prepared by a state-licensed compounding pharmacy and tailored to the treatment plan your doctor creates.

Questions we hear everyday

Do I need to make changes to my diet with Compound Tirzepatide?

We believe in a sustainable and flexible approach to nutrition, without imposing limitations on your diet. Our goal is to guide you in establishing healthy eating habits, complemented by the medication's ability to decrease appetite and 'food noise.' We encourage maintaining a nourishing, high-protein diet, and many patients report losing weight without needing uncomfortably restrictive dieting or calorie counting.

What are the side effects for Tirzepatide?

Common side effects of semaglutide are usually mild and may include:

• Nausea

• Vomiting

• Diarrhea

• Constipation

• Abdominal pain

• Decreased appetite

• Indigestion


The majority of side effects are transient and typically resolve spontaneously. Nevertheless, if side effects persist or deteriorate, seek guidance from a healthcare professional.

Willow also offers Odansetron to manage side effects if they occur. This medication is commonly used to prevent nausea and vomiting.

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Tirzepatide Patient Safety Information

What happens if I stop the medication?

When stopping Tirzepatide abruptly, some patients may experience mild to moderate weight gain. Others may maintain the weight loss they achieved while on the medication. We recommend patients work with their Willow physician to slowly decrease their dose in order to maintain their weight loss achievements.

You may notice an increase in appetite and a return of food cravings, allowing you to eat more without feeling as full. By gradually tapering off the medication with your physician’s guidance, you can better manage these changes and maintain your health and wellness goals.

How do I take Tirzepatide?

Tirzepatide is administered once a week via a subcutaneous injection. Don’t worry! The needle is very small and short, making self-injection quick & easy. We’ll provide you with detailed written and video instructions that make the process simple and easy to follow. We even include a link to a soothing Spotify playlist to play in the background if you wish.

More from our members

4.9/5 (2200 + 5 star reviews)
"I'm a registered dietitian and know how to eat healthy and exercise but I gained 20 pounds after menopause and had a tough time getting that weight off. I used the injectables and within 5 months have lost 20 pounds. I have a regular biking/walking program now that it's summer so with diet, meds and exercise, the weight has come off nicely. Customer service has been great and responses within 1 day. Great experience all around!"
Becky U.
"Willow is hands down the best decision I've made for my health! The semaglutide injections have made it so much easier to lose weight, I don't feel hungry all the time, and I don't obsess over food anymore. I've lost 30 lbs, and I'm feeling more confident every day. Plus, their customer service is fantastic! 10/10 recommend!"
Ana O.
"I was 100% satisfied with the experience, then Willow managed to improve the experience even more when a non-weight loss related issue came up suddenly. I could not have asked for better response time & actions taken. I'm so happy I chose Willow given all of the providers out there."
Susan K.
"Nothing but a good experience with Willow. I'm almost to my goal weight. I've lost 25 lbs. From the doctors to the staff everyone is great and very responsive. I've referred a friend and she is having a great experience too. Highly recommended!"
Olga C.
"I've been using Willow for 4 months now and although they are a bit more expensive than other sites for GLP, I am sticking with them because I appreciate the fast response and personal physician care. Many other sites just dole out meds unsupervised and it's impossible to get a hold of a human. I also feel like their GLP combo with Vitamin B is really helpful."
Meg T.
"Really good experience with the Willow team. They understood my issues and helped me stay motivated. The options are easy and the meal suggestions are tasty which easily helps when trying new things. It has been more about learning way of life and habit building for me so this was all really helpful."
Rudi V.
"I've had such a great experience from start to finish. The customer service is outstanding (thanks Mallory) and every question I had for the doctor or the team was answered quickly and with real care. Thanks to their support, I've reached my goal and finally lost the weight I couldn't lose on my own. I highly recommend them to anyone on a similar journey!"
Romy H.
"This is the first time in YEARS that I've enjoyed looking in the mirror! I've lost 22 lbs, but more than that, my confidence has been restored. The support from their team is amazing (shoutout Jethel and Dr Green), and I love how easy it is to adjust shipments. Seriously, if you're on the fence, just go for it!"
Megan C.