SLP-1
A prescription chewable that works with your body’s own sleep clock, not against it. Made for adults who have trouble falling asleep.
SLP-1
A prescription chewable that works with your body’s own sleep clock, not against it. Made for adults who have trouble falling asleep.
Fall asleep faster, even when your mind won’t switch off
Drift off without feeling knocked out, with no next-day grogginess
Non-habit-forming, not a controlled substance and made for nightly use
SLP-1 is a doctor-prescribed mint chewable tablet that helps you fall asleep. It contains ramelteon, the active ingredient in an FDA-approved sleep medication, plus magnesium glycinate and DHHB, chosen to complement it.
Instead of sedating the brain like most prescription sleeping pills, ramelteon targets the melatonin receptors that regulate your sleep-wake cycle. Magnesium glycinate is a well-absorbed form of magnesium, a mineral involved in muscle relaxation and nerve function. DHHB is a natural bioactive compound traditionally used as part of an evening wind-down.
SLP-1 is a compounded medication, and compounded medications aren’t FDA-approved.
Falling asleep faster
SLP-1 is made to help you fall asleep faster, even when your mind won’t switch off. Drift off, don’t get knocked out.
Waking up like yourself
Sleep well, then wake up like yourself, with no next-day grogginess.
Better days
Sleep better, look and feel better. That can mean more patience for your day, and for the people in it.
Individual results may vary.
May cause drowsiness. Don’t drive or drink alcohol after taking.
SLP-1 may be a good fit for adults with mild to moderate sleep issues, mainly trouble falling asleep. It’s often a good option for people who:
- feel their mind switch on the moment their head hits the pillow
- have tried the usual fixes without the results they want
- want something that isn’t a heavy sleeping pill
- feel tired but wired at night
SLP-1 is not appropriate for everyone. You should not take it if you take fluvoxamine (Luvox), are pregnant or breastfeeding, have diabetes or liver or kidney disease or have had a serious allergic reaction to ramelteon. If you have sleep apnea, your doctor will review it first, since SLP-1 is not designed to treat this condition.
SLP-1 may be prescribed to eligible adults ages 18 to 75. A Willow doctor will review your health history and determine if treatment is right for you.
Possibly, and your doctor will check. During your online assessment, you’ll share your health history and any medications or supplements you take. Your Willow doctor reviews them for possible interactions before prescribing, and you can message them if anything changes after you start.
Take 1 chewable tablet about 30 minutes before you plan to sleep, at about the same time each night. Chew it completely before swallowing, no water needed, and skip big or high-fat meals right beforehand since food can slow it down.
The Willow difference
The science behind SLP-1
Most prescription sleeping pills act on GABA-A, a receptor that quiets the brain broadly. Ramelteon has no meaningful effect on it. A traditional sleeping pill flips the breaker for the whole house. SLP-1 dims the lights in the one room that needs it, and it does its work at the start of the night.
Ramelteon has a track record. In a six-month study of 451 adults with chronic insomnia, it helped people fall asleep faster than placebo at every check-in. Those results are from studies of ramelteon on its own.
What to expect from SLP-1
Bedtime that doesn’t turn into a battle with their own brain
Drifting off instead of running through tomorrow’s to-do list
Less of that tired-but-wired feeling at night
No second thoughts about taking it again tomorrow night
A note from Dr. Green
If you want to look and feel your best, there’s no single way to get there. When a plan fits your body and your life, it can help you feel more confident and comfortable in your own skin.
That’s why we build your treatment plan around you. You shouldn’t have to adjust to your care. Your care should adjust to you.
Prescription treatment
Guided by doctors
Judgement-free care
What patients say about Willow
SLP-1 FAQs
Your SLP-1 prescription includes a one-month supply of 30 chewable tablets, or a three-month supply of 90 chewable tablets. Your medication is prepared by the pharmacy and shipped to you in discreet packaging. You’ll also have support from your Willow doctor and the Care Team.
Experiences and timelines vary from patient to patient, and no specific result can be promised. SLP-1 is taken about 30 minutes before bed and kicks in as you settle in. If falling asleep isn’t getting easier, message your Willow doctor.
Store SLP-1 at room temperature, away from heat and moisture, and out of reach of children. Use it by the date on the label.
Yes. Your Willow doctor can adjust your treatment as your needs change, and you can cancel anytime. Message your doctor to discuss your options.
Like any prescription treatment, SLP-1 can cause side effects. The most common are drowsiness, dizziness, tiredness and nausea. Stop taking it and contact your doctor right away if you notice unusual behavior during sleep (like sleep-walking or sleep-driving), worsening mood or swelling of the face, lips or throat. Full details can be found in our Patient Safety Information.
