GHK-Cu 3% Cream
Support your skin with a prescription copper peptide cream, 3% GHK-Cu, the copper-bound form of a peptide found naturally in the body.





GHK-Cu 3% Cream
Support your skin with a prescription copper peptide cream, 3% GHK-Cu, the copper-bound form of a peptide found naturally in the body.
Firmer-looking skin, one thin layer at a time
Smoother-looking texture on your face and neck
A routine that feels like a plan, not a pile of products
GHK-Cu 3% Cream is a doctor-prescribed copper peptide cream for your face and neck. It contains 3% GHK-Cu, the copper-bound form of a peptide found naturally in the body, to support firmer-looking skin and smoother-looking texture.
Each bottle is made with GHK-Cu (copper tripeptide-1) at 3% (30mg/g) in a cream base. It’s compounded by a licensed U.S. pharmacy and prescribed by your Willow doctor.
GHK-Cu 3% Cream is a compounded medication, and compounded medications aren’t FDA-approved.
Firmer-looking skin & smoother-looking texture
GHK-Cu 3% Cream supports firmer-looking skin and smoother-looking texture. It’s one thin layer on your face and neck, once or twice a day.
Fits into your routine
It’s made to work around tretinoin, with GHK-Cu in the morning and tretinoin at night. Your Willow doctor adds it to your personalized protocol, so it fits with the rest of your routine.
Three months in one bottle
One pump bottle is a 90-day supply, so you’re set for three months.
Individual results may vary.
May cause skin redness or irritation. Not for use during pregnancy or breastfeeding.
GHK-Cu 3% Cream may be a good fit for adults who want firmer-looking skin and smoother-looking texture. It’s often a consideration for people who:
- have tried the usual shelf fixes and want a plan, not another product
- want a doctor’s opinion on their skin, without the waiting room
- are looking to add a prescription option to their routine, tretinoin included
- don’t want to feel judged for caring how their skin looks
You should not use it if you:
- are pregnant or breastfeeding
- have diabetes or Wilson’s disease
- are allergic to copper or any ingredient
You should never apply to broken or infected skin.
GHK-Cu 3% Cream may be prescribed to eligible adults 18 and older. A Willow doctor will review your health history and determine if treatment is right for you.
Possibly, and your Willow doctor will help you decide. GHK-Cu 3% Cream is made to work around Tretinoin, so the two can typically be used in the same skincare routine.
Your doctor will review your health history and any medications you take before prescribing, and can discuss whether adding a second treatment, like tretinoin, makes sense for you.
Apply a thin layer to your face and neck once or twice a day. If you also use tretinoin, use GHK-Cu in the morning and tretinoin at night, so the two are never applied at the same time. Strong acids and vitamin C also shouldn’t be layered with GHK-Cu.

The Willow difference
The science behind
GHK-Cu 3% Cream
GHK-Cu 3% Cream is compounded by a licensed U.S. pharmacy to the strength your Willow doctor prescribes, so it’s a prescription treatment, not an off-the-shelf product.
Added to your routine, it gives you one clear step to build around, instead of another serum to guess at.
What to expect from GHK-Cu 3% Cream
Skin that looks firmer and more even-toned
A more youthful appearance over time
Feeling confident in their skin, with or without makeup
A look that’s still them, just a bit more polished
A note from Dr. Green
If you want to look and feel your best, there’s no single way to get there. When a plan fits your body and your life, it can help you feel more confident and comfortable in your own skin.
That’s why we build your treatment plan around you. You shouldn’t have to adjust to your care. Your care should adjust to you.
What patients say about Willow
GHK-Cu 3% Cream FAQs
Your GHK-Cu 3% Cream includes one 30 mL pump bottle, which is a 90-day supply. It is prepared by the pharmacy and shipped to you in discreet packaging. You’ll also have support from your Willow doctor and the Care Team.
Experiences and timelines vary from patient to patient, and how your skin adjusts to the product will shape when you notice changes. Apply a thin layer to your face and neck once or twice a day, depending on your prescription. If you have questions about how your skin is responding, message your Willow doctor.
Store GHK-Cu 3% Cream at room temperature, between 68°F and 77°F. Use it by the date on the label.
Yes. Your Willow doctor can adjust your treatment as your needs change, and you can cancel anytime. Message your doctor to discuss your options.
Like any prescription treatment, GHK-Cu 3% Cream can cause side effects. The most common are redness, irritation, itching and dryness where applied. Stop using it and contact your doctor if you get a rash, swelling or severe irritation. Full details can be found in our Patient Safety Information.
















