GHK-Cu 3% Cream

Firmer-looking skin, smoother-looking texture

Support your skin with a prescription copper peptide cream, 3% GHK-Cu, the copper-bound form of a peptide found naturally in the body.

GHK-Cu 3% Cream

Firmer-looking skin, smoother-looking texture

Support your skin with a prescription copper peptide cream, 3% GHK-Cu, the copper-bound form of a peptide found naturally in the body.
$199/90-day supply

Firmer-looking skin, one thin layer at a time

Smoother-looking texture on your face and neck

A routine that feels like a plan, not a pile of products

Trusted by 100,000+ patients.
100% online care
Doctor-prescribed
Pharmacy-prepared
Same-day assessment
Free shipping
24/7 support
100% online care
Doctor-prescribed
Pharmacy-prepared
Same-day assessment
Free shipping
24/7 support
What is GHK-Cu 3% Cream?

GHK-Cu 3% Cream is a doctor-prescribed copper peptide cream for your face and neck. It contains 3% GHK-Cu, the copper-bound form of a peptide found naturally in the body, to support firmer-looking skin and smoother-looking texture.

Each bottle is made with GHK-Cu (copper tripeptide-1) at 3% (30mg/g) in a cream base. It’s compounded by a licensed U.S. pharmacy and prescribed by your Willow doctor.

GHK-Cu 3% Cream is a compounded medication, and compounded medications aren’t FDA-approved.

Benefits

Firmer-looking skin & smoother-looking texture

GHK-Cu 3% Cream supports firmer-looking skin and smoother-looking texture. It’s one thin layer on your face and neck, once or twice a day.

Fits into your routine

It’s made to work around tretinoin, with GHK-Cu in the morning and tretinoin at night. Your Willow doctor adds it to your personalized protocol, so it fits with the rest of your routine.

Three months in one bottle

One pump bottle is a 90-day supply, so you’re set for three months.

Individual results may vary.

May cause skin redness or irritation. Not for use during pregnancy or breastfeeding.

Who should use GHK-Cu 3% Cream?

GHK-Cu 3% Cream may be a good fit for adults who want firmer-looking skin and smoother-looking texture. It’s often a consideration for people who:

  • have tried the usual shelf fixes and want a plan, not another product
  • want a doctor’s opinion on their skin, without the waiting room
  • are looking to add a prescription option to their routine, tretinoin included
  • don’t want to feel judged for caring how their skin looks

‍

You should not use it if you:

  • are pregnant or breastfeeding
  • have diabetes or Wilson’s disease
  • are allergic to copper or any ingredient

‍

You should never apply to broken or infected skin.

GHK-Cu 3% Cream may be prescribed to eligible adults 18 and older. A Willow doctor will review your health history and determine if treatment is right for you.

Can I use GHK-Cu 3% Cream with other treatments?

Possibly, and your Willow doctor will help you decide. GHK-Cu 3% Cream is made to work around Tretinoin, so the two can typically be used in the same skincare routine. 

Your doctor will review your health history and any medications you take before prescribing, and can discuss whether adding a second treatment, like tretinoin, makes sense for you.

How do I apply GHK-Cu 3% Cream?

Apply a thin layer to your face and neck once or twice a day. If you also use tretinoin, use GHK-Cu in the morning and tretinoin at night, so the two are never applied at the same time. Strong acids and vitamin C also shouldn’t be layered with GHK-Cu.

The Willow difference

US-licensed doctors
Transparent pricing, no hidden fees
Needle-free options
24/7 human support
Zero judgment
Others
Nurse practitioners or physician assistants
Add-on fees for visits or follow-ups
Injectable only
AI-powered support
Comes with a lecture

The secret isn’t another serum

You’ve got plenty on the shelf already.
It’s time for a plan, not another product.

The science behind

‍GHK-Cu 3% Cream

GHK-Cu is a copper peptide, a small molecule made of amino acids bound to copper. It’s a form of a peptide found naturally in the body.

GHK-Cu 3% Cream is compounded by a licensed U.S. pharmacy to the strength your Willow doctor prescribes, so it’s a prescription treatment, not an off-the-shelf product.

Added to your routine, it gives you one clear step to build around, instead of another serum to guess at.

What to expect from GHK-Cu 3% Cream

Patients may notice:

Skin that looks firmer and more even-toned

A more youthful appearance over time

Feeling confident in their skin, with or without makeup

A look that’s still them, just a bit more polished

Getting started with Willow

Three simple steps to get started

1
Assessment
and review
FSA & HSA eligible
Answer a few questions about your health and goals. A US-licensed physician reviews your assessment, usually within 24 hours. If treatment is right for you, they'll confirm your prescription.
FSA & HSA eligible
2
Preparation
and shipping
Your prescription is prepared by trusted US pharmacy partners. It ships with tracking, so you always know where it is.
FSA & HSA eligible
3
Delivery
and support
Your treatment arrives in discreet packaging. From there, you'll have unlimited doctor messaging and 24/7 Care Team support.
FSA & HSA eligible

Getting started with Willow

Three simple steps to weight loss care
1
Assessment and review
Answer a few questions about your health and goals. A US-licensed physician reviews your assessment, usually within 24 hours. If treatment is right for you, they'll confirm your prescription.
FSA & HSA eligible
2
Preparation and shipping
Your prescription is prepared by trusted US pharmacy partners. It ships with tracking, so you always know where it is.
FSA & HSA eligible
3
Delivery and support
Your treatment arrives in discreet packaging. From there, you'll have unlimited doctor messaging and 24/7 Care Team support.
FSA & HSA eligible

A note from Dr. Green

As Willow’s Chief Medical Officer, I look closely at how treatments hold up in real life, beyond how they perform on paper.

If you want to look and feel your best, there’s no single way to get there. When a plan fits your body and your life, it can help you feel more confident and comfortable in your own skin. 

That’s why we build your treatment plan around you. You shouldn’t have to adjust to your care. Your care should adjust to you.
Individual results may vary.

Prescription treatment

Medication chosen around your health history and goals, with a treatment plan built for you.

Guided by doctors

Every Willow prescriber is a U.S. licensed physician who oversees your treatment and adjusts it as needed.

Judgement-free care

No office visits. 100% online. Access to your doctor and the Willow Patient Care Services Team whenever you need it.

What patients say about Willow

4.9/5 (2200 + 5 star reviews)
"I was 100% satisfied with the experience, then Willow managed to improve the experience even more when a non-weight loss related issue came up suddenly. I could not have asked for better response time & actions taken. I'm so happy I chose Willow given all of the providers out there."
Susan K.
"Nothing but a good experience with Willow. I'm almost to my goal weight. I've lost 25 lbs. From the doctors to the staff everyone is great and very responsive. I've referred a friend and she is having a great experience too. Highly recommended!"
Olga C.
"I’m super happy with using Willow so far. The medication really works well, their doctors are always responsive and ready to help. Their customer service email seems to be working 24/7 and they are always super helpful and flexible."
Natalja M.
"Love everything about my experience with Willow. I felt my issues were taken seriously and addressed quickly and with respect. The level of communication means I know any issues or concerns will be taken care of in a short amount of time. Not to mention the relief of my menopause symptoms with the prescriptions given to me."
Lisa G.
"Great and seamless experience, highly dependable delivery and product. And always available staff for any consultation or advice."
Anka

GHK-Cu 3% Cream FAQs

What’s included?

Your GHK-Cu 3% Cream includes one 30 mL pump bottle, which is a 90-day supply. It is prepared by the pharmacy and shipped to you in discreet packaging. You’ll also have support from your Willow doctor and the Care Team.

When will I notice results?

Experiences and timelines vary from patient to patient, and how your skin adjusts to the product will shape when you notice changes. Apply a thin layer to your face and neck once or twice a day, depending on your prescription. If you have questions about how your skin is responding, message your Willow doctor.

How should I store GHK-Cu 3% Cream?

Store GHK-Cu 3% Cream at room temperature, between 68°F and 77°F. Use it by the date on the label.

Can I change or cancel my treatment plan?

Yes. Your Willow doctor can adjust your treatment as your needs change, and you can cancel anytime. Message your doctor to discuss your options.

Are there any side effects?

Like any prescription treatment, GHK-Cu 3% Cream can cause side effects. The most common are redness, irritation, itching and dryness where applied. Stop using it and contact your doctor if you get a rash, swelling or severe irritation. Full details can be found in our Patient Safety Information.

When you feel better, it shows

In the way you see yourself, and the confidence you carry with you.